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Originally published January 10, 2010 at 10:00 PM | Page modified January 10, 2010 at 11:59 PM

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2010 may be strong year for 'cleantech'

Codexis is one of those Silicon Valley companies that might be considered stealthy by accident — deeply scientific and hard to categorize, it develops biocatalysts to make pharmaceuticals, chemicals and biofuels. It's the "cleantech" angle that might make Codexis sizzle with investors, even if its enzymes will never be as sexy as Tesla's roadsters.

San Jose Mercury News

Shades of green

In 2009, Greentech Media tabulated $4.85 billion worth of cleantech venture-capital investments into 356 deals, covering 18 categories. Here are the top six by dollar amount.

Solar: $1.41 billion into 84 deals

Biofuels: $985 million into 44 deals

Automotive, transportation: $553 million into 29 deals

Batteries, storage: $455 million into 36 deals

Green buildings: $143 million into 10 deals

Wind: $142 million into 17 deals

Source: Greentech Media

When a Redwood City, Calif., company called Codexis disclosed last week that it had filed documents in preparation of a Wall Street offering, some people said, "Co-who?"

Codexis is one of those Silicon Valley companies that might be considered stealthy by accident — deeply scientific and hard to categorize, it develops biocatalysts to make pharmaceuticals, chemicals and biofuels. It's the "cleantech" angle that might make Codexis sizzle with investors, even if its enzymes will never be as sexy as Tesla's roadsters.

For some start-of-the-year crystal-ball gazing, this amateur futurist will echo cleantech venture capitalists like Erik Straser, of Mohr Davidow Ventures, and Ira Ehrenpreis, of Technology Green Energy Partners, in forecasting a rousing 2010 for cleantech IPOs, mergers and acquisitions, and venture investments.

The latest sign that clean, green mojo is back is a report from Greentech Media that found venture investments in "green" technologies totaled $4.85 billion in 356 deals in 2009. That was down from $7.6 billion in 350 deals in 2008, but still a strong showing in the aftermath of the financial crisis. The 2009 sum was nearly $1.5 billion more than the amount invested in 2007, before the worst economic collapse since the 1930s struck.

Greentech Media is one of several outfits — including Cleantech Group, Deloitte and PricewaterhouseCoopers — that have tabulated cleantech investments in recent years. The numbers don't match, in part because different outfits use different definitions of what constitutes a "clean" or "green" technology, Greentech's Eric Wesoff said. But the various reports, he added, always have agreed on the broad trends.

Solar power, as it has been for the last four years, was the leading investment segment in Greentech's report, attracting $1.4 billion in 84 deals. The runner up was biofuels, which attracted $976 million in 44 deals.

The IPO filing by Codexis, a biofuel play from the cleantech perspective, comes on the heels of a recent filing by Solyndra, a Fremont, Calif., solar startup with a decidedly higher profile. In addition to hefty venture funding, Solyndra, founded in 2005, received a $535 million federal loan guarantee earlier this year. In September, it began building a second solar-panel manufacturing plant designed to produce 500 megawatts per year and fulfill its $2 billion backlog of contracts, the company said.

Different path

Codexis took a different path to Wall Street. In 2002, it was spun out of Maxygen, a biotech firm that developed a process it calls MolecularBreeding to develop pharmaceuticals. The news release that unveiled Codexis emphasized its aim to be "a leading provider of high-value chemical products and services to the worldwide life science and fine chemical industry," but there were no overt reference to biofuels, carbon reduction or other clean, green themes.

In 2003, Codexis announced a collaboration with Cargill for a biofuel research project funded by an award from the Department of Energy. Today, its Web site emphasizes not only biofuels but also its role in the emerging cleantech markets of carbon capture and safe water.

Codexis reported $50.5 million in revenue in 2008, and $58.7 million in the first nine months of 2009; it had a net loss of $15.1 million from January to September of last year. The company is aiming to raise up to $100 million in an IPO, a relatively modest sum.

Common investor

In pursuing a Wall Street debut, Codexis and Solyndra would be following the recent successful IPO of A123 Systems, a Massachusetts-based maker of lithium-ion-battery technology. The three companies share a common investor: CMEA Ventures. Thomas Baruch, who founded CMEA in 1989, is the chairman of Codexis.

With one successful cleantech IPO and two more in the pipeline, "CMEA is on a little bit of a roll right now," said Greentech's Wesoff.

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